Publication Beamlines Strategic Pillar
Sack, John S.; Gao, Mian; Kiefer, Susan E.; Myers, Joseph E.; Newitt, John A. et al. (2016). Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor. Acta Crystallographica Section F:Structural Biology Communications 72(2) , 129-134. 10.1107/s2053230x15024747. [PDB: 5es1] CMCF-ID Health
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] CMCF-ID Health
Skovpen, Yulia V.; Conly, Cuylar J. T.; Sanders, David A. R.; Palmer, David R. J. (2016). Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. Journal of the American Chemical Society 138(6) , 2014-2020. 10.1021/jacs.5b12695. [PDB: 5f1u, 5f1v] CMCF-ID Health
Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. [PDB: 5i83, 5i86] CMCF-ID Health
Wheatley, Robert W.; Ng, Kenneth K.S.; Kapoor, Manju (2016). Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa. Archives of Biochemistry and Biophysics 590, 125-137. 10.1016/j.abb.2015.11.037. [PDB: 4zty] CMCF-ID Health
Wu, Wen-Lian; Hao, Jinsong; Domalski, Martin; Burnett, Duane A.; Pissarnitski, Dmitri et al. (2016). Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. ACS Medicinal Chemistry Letters 7(5) , 498-501. 10.1021/acsmedchemlett.6b00027. [PDB: 5i7u] CMCF-ID Health
Conly; Cuylar (2016). Determination of the Structural Allosteric Inhibitory Mechanism of Dihydrodipicolinate Synthase. Supervisor: Sanders, David A.; Palmer, David R.. SK, Canada: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2015-11-2317. CMCF-BM, CMCF-ID Health
Aydin, H.; Lee, J.E. (2016). Crystal structure of the ASLV fusion protein core. Protein Data Bank: 5h9c. CMCF-ID Health
Beyrakhova, K.; van Straaten, K.; Cygler, M. (2016). Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila. Protein Data Bank: 5fia. CMCF-ID Health
Bloudoff, K.; Alonzo, D.A.; Schmeing, T.M. (2016). First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a. Protein Data Bank: 5du9. CMCF-ID Health
Bloudoff, K.; Alonzo, D.A.; Schmeing, T.M. (2016). First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 3a. Protein Data Bank: 5dua. CMCF-ID Health
Burke, J.E.; Fowler, M.L. (2016). Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11. Protein Data Bank: 5euq. CMCF-ID Health
Chaudet, M.M.; Rose, D.R. (2016). Crystal structure of Family 31 alpha-glucosidase (BT_3299) from Bacteroides thetaiotaomicron. Protein Data Bank: 5djw. CMCF-ID Health
Chaudet, M.M.; Rose, D.R. (2016). Crystal structure of Family 31 alpha-glucosidase (BT_0339) from Bacteroides thetaiotaomicron. Protein Data Bank: 5f7c. CMCF-ID Health
Grigg, J.C.; Kobylarz, M.J.; Liu, Y.; Lee, M.S.F.; Heinrichs, D.E. et al. (2016). Staphyloferrin B precursor biosynthetic enzyme SbnA bound to PLP. Protein Data Bank: 5d84. CMCF-ID Health