Publication Beamlines Strategic Pillar
Beyrakhova, Ksenia; Li, Lei; Xu, Caishuang; Gagarinova, Alla; Cygler, Miroslaw et al. (2018). Legionella pneumophilaeffector Lem4 is a membrane-associated protein tyrosine phosphatase. Journal of Biological Chemistry 293(34) , 13044-13058. 10.1074/jbc.ra118.003845. [PDB: 6cdw, 6cgj] CMCF-ID Health
Blackler, Ryan J.; López-Guzmán, Arturo; Hager, Fiona F.; Janesch, Bettina; Martinz, Gudrun et al. (2018). Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Nature Communications 9(1) . 10.1038/s41467-018-05471-3. [PDB: 6cwc, 6cwh, 6cwi, 6cwl, 6cwm, 6cwn, 6cwr] CMCF-ID Agriculture
Chen, Yun; Murillo-Solano, Claribel; Kirkpatrick, Melanie G.; Antoshchenko, Tetyana; Park, Hee-Won et al. (2018). Repurposing drugs to target the malaria parasite unfolding protein response. Scientific Reports 8(1) . 10.1038/s41598-018-28608-2. CMCF-ID Health
González, Javier M.; Marti-Arbona, Ricardo; Chen, Julian C.-H.; Broom-Peltz, Brian; Unkefer, Clifford J. et al. (2018). Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase. Acta Crystallographica Section F:Structural Biology Communications 74(10) , 610-616. 10.1107/s2053230x18011809. [PDB: 5ujk] CMCF-ID Health
Jenkins, Meredith L.; Margaria, Jean Piero; Stariha, Jordan T. B.; Hoffmann, Reece M.; McPhail, Jacob A. et al. (2018). Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5. Nature Communications 9(1) . 10.1038/s41467-018-06196-z. [PDB: 6djl] CMCF-ID Health
Kallander, Lara S.; Washburn, David; Hilfiker, Mark A.; Eidam, Hilary Schenck; Lawhorn, Brian G. et al. (2018). Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1. ACS Medicinal Chemistry Letters 9(7) , 736-740. 10.1021/acsmedchemlett.8b00173. [PDB: 6bsm] CMCF-ID Health
King, Moeko Toride; Huh, Ian; Shenai, Akhilesh; Brooks, Teresa M.; Brooks, Cory L. et al. (2018). Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes. Journal of Biological Chemistry 293(35) , 13626-13635. 10.1074/jbc.ra118.003888. [PDB: 6dba, 6dbd, 6dbe, 6dbf, 6dbg] CMCF-ID Health
Labriola, Jonathan M.; Zhou, Yifan; Nagar, Bhushan (2018). Structural Analysis of the Bacterial Effector AvrA Identifies a Critical Helix Involved in Substrate Recognition. Biochemistry 57(33) , 4985-4996. 10.1021/acs.biochem.8b00512. [PDB: 6be0] CMCF-ID Health
Lacbay, Cyrus M.; Waller, Daniel D.; Park, Jaeok; Gómez Palou, Mònica; Vincent, Félix et al. (2018). Unraveling the Prenylation–Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. Journal of Medicinal Chemistry 61(15) , 6904-6917. 10.1021/acs.jmedchem.8b00886. [PDB: 6c56, 6c57] CMCF-ID Health
Sauvé, Véronique; Sung, George; Soya, Naoto; Kozlov, Guennadi; Blaimschein, Nina et al. (2018). Mechanism of parkin activation by phosphorylation. Nature Structural and Molecular Biology 25(7) , 623-630. 10.1038/s41594-018-0088-7. [PDB: 6djw, 6djx] CMCF-ID Health
Smith, Peter A.; Koehler, Michael F. T.; Girgis, Hany S.; Yan, Donghong; Chen, Yongsheng et al. (2018). Optimized arylomycins are a new class of Gram-negative antibiotics. Nature 561(7722) , 189-194. 10.1038/s41586-018-0483-6. [PDB: 6b88] CMCF-ID Health
Tanaka, Hiroshi; Sase, Hitoshi; Tsukaguchi, Toshiyuki; Hasegawa, Masami; Tanimura, Hiromi et al. (2018). Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer. Molecular Cancer Therapeutics 17(12) , 2519-2529. 10.1158/1535-7163.mct-17-1180. [PDB: 5wr7] CMCF-ID Health
Tarade, Daniel; Robinson, Claire M.; Lee, Jeffrey E.; Ohh, Michael (2018). HIF-2α-pVHL complex reveals broad genotype-phenotype correlations in HIF-2α-driven disease. Nature Communications 9(1) . 10.1038/s41467-018-05554-1. [PDB: 6bvb] CMCF-ID Health
Trofimova, Daria; Paydar, Mohammadjavad; Zara, Anthony; Talje, Lama; Kwok, Benjamin H. et al. (2018). Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate. Nature Communications 9(1) . 10.1038/s41467-018-05025-7. [PDB: 6bbn] CMCF-ID Health
Zara; Anthony (2018). Characterization of the interactions of a lignostilbene alpha-beta dioxygenase with both stilbene and carotenoid substrates. Supervisor: Loewen, Michele; Allingham, John. Ontario, Canada: Queen's University. http://hdl.handle.net/1974/24890. CMCF-ID Health