Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Gassaway, Brandon M.; Cardone, Rebecca L.; Padyana, Anil K.; Petersen, Max C.; Judd, Evan T. et al. (2019). Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Reports 29(11) , 3394-3404.e9. 10.1016/j.celrep.2019.11.009. [PDB: 6ech] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Herrmann, Jonathan; Li, Po-Nan; Jabbarpour, Fatemeh; Chan, Anson C. K.; Rajkovic, Ivan et al. (2019). A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proceedings of the National Academy of Sciences of the United States of America 117(1) , 388-394. 10.1073/pnas.1909798116. [PDB: 6p5t] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hettle, Andrew G.; Hobbs, Joanne K.; Pluvinage, Benjamin; Vickers, Chelsea; Abe, Kento T. et al. (2019). Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species. Communications Biology 2(1) . 10.1038/s42003-019-0721-y. [PDB: 6pnu, 6pop, 6prm, 6psm, 6pt4, 6ptk] |
CMCF-ID |
Peer-Reviewed Article |
Environment |
Li, Zhijie; Tomlinson, Aidan CA; Wong, Alan HM; Zhou, Dongxia; Desforges, Marc et al. (2019). The human coronavirus HCoV-229E S-protein structure and receptor binding. eLife 8. 10.7554/elife.51230. [PDB: 6u7e, 6u7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
McCallum, Matthew; Benlekbir, Samir; Nguyen, Sheryl; Tammam, Stephanie; Rubinstein, John L. et al. (2019). Multiple conformations facilitate PilT function in the type IV pilus. Nature Communications 10(1) . 10.1038/s41467-019-13070-z. [PDB: 6ojy, 6okv] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Reimer, Janice M.; Eivaskhani, Maximilian; Harb, Ingrid; Guarné, Alba; Weigt, Martin et al. (2019). Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science 366(6466) , eaaw4388. 10.1126/science.aaw4388. [PDB: 6mfw, 6mfx, 6mfy, 6mfz] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Rescourio, Gwenaella; Gonzalez, Ana Z.; Jabri, Salman; Belmontes, Brian; Moody, Gordon et al. (2019). Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. Journal of Medicinal Chemistry 62(22) , 10258-10271. 10.1021/acs.jmedchem.9b01310. [PDB: 6ud2, 6udi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Tarry, Michael J.; Harmel, Christoph; Taylor, James A.; Marczynski, Gregory T.; Schmeing, T. Martin et al. (2019). Structures of GapR reveal a central channel which could accommodate B-DNA. Scientific Reports 9(1) . 10.1038/s41598-019-52964-2. [PDB: 6ozx, 6ozy, 6ozz] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wei, Yong; Resetca, Diana; Li, Zhe; Johansson-Åkhe, Isak; Ahlner, Alexandra et al. (2019). Multiple direct interactions of TBP with the MYC oncoprotein. Nature Structural and Molecular Biology 26(11) , 1035-1043. 10.1038/s41594-019-0321-z. [PDB: 6e24] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Grant; Benjamin Micah Milrod (2019). Calmodulin Disrupts Plasma Membrane Localization of Farnesylated KRAS4b by Sequestering its Lipid Moiety. Supervisor: Ikura, Mitsuhiko. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/98053. |
CMCF-ID |
Masters Thesis |
Agriculture |
Boniecki, M.T.; Cygler, M. (2019). Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2. Protein Data Bank: 6uxe. |
CMCF-ID |
PDB Deposition |
Agriculture |
Chen, Y.S.; Gehring, K. (2019). Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+. Protein Data Bank: 6n7e. |
CMCF-ID |
PDB Deposition |
Agriculture |
Dong, C.; Tempel, W.; Walker, J.R.; Bountra, C.; Arrowsmith, C.H. et al. (2019). Crystal structure of CDYL2 in complex with H3tK27me3. Protein Data Bank: 6v2h. |
CMCF-ID |
PDB Deposition |
Agriculture |
Huang, X.; Whittington, D. (2019). X-ray co-crystal structure of compound 20 with Mcl-1. Protein Data Bank: 6udi. |
CMCF-ID |
PDB Deposition |
Health |