Publication Beamlines Strategic Pillar
Candito, David A.; Simov, Vladimir; Gulati, Anmol; Kattar, Solomon; Chau, Ryan W. et al. (2022). Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry 65(24) , 16801-16817. 10.1021/acs.jmedchem.2c01605. [PDB: 8e80] CMCF-ID Health
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. [PDB: 8csb, 8csc, 8csd, 8cse, 8csf] CMCF-BM, CMCF-ID Health
Hallett, Robin M.; Bonfill-Teixidor, Ester; Iurlaro, Raffaella; Arias, Alexandra; Raman, Swetha et al. (2022). Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment. Clinical Cancer Research 29(4) , 791-804. 10.1158/1078-0432.ccr-21-1888. CMCF-ID Agriculture
Kim, Hyeong Jin; Black, Mazzen; Edwards, Ross A.; Peillard-Fiorente, Flora; Panigrahi, Rashmi et al. (2022). Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones. Nature Communications 13(1) . 10.1038/s41467-022-34875-5. [PDB: 7rgt] CMCF-ID Health
Li, Kunhua; Tokareva, Olena S.; Thomson, Ty M.; Wahl, Sebastian C. T.; Travaline, Tara L. et al. (2022). De novo mapping of α-helix recognition sites on protein surfaces using unbiased libraries. Proceedings of the National Academy of Sciences of the United States of America 119(52) . 10.1073/pnas.2210435119. [PDB: 7uwi] CMCF-ID Health
Luan, Xiaodong; Li, Xinming; Li, Yufan; Su, Gengchen; Yin, Wanchao et al. (2022). Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Science Bulletin 67(22) , 2327-2335. 10.1016/j.scib.2022.10.021. [PDB: 7xwz] CMCF-ID Health
Brennan, M.; Agarwal, S.; Thomson, T.; Wahl, S.; Ramirez, J. et al. (2022). Structure of beta-catenin in complex with FP01567, a Helicon Polypeptide. Protein Data Bank: 7uwi. CMCF-ID Health
Forrester, T.J.B.; Kimber, M.S. (2022). WbbB D232C Kdo adduct. Protein Data Bank: 8csd. CMCF-ID Agriculture
Forrester, T.J.B.; Kimber, M.S. (2022). WbbB D232N in complex with CMP-beta-Kdo. Protein Data Bank: 8csb. CMCF-ID Agriculture
Gunn, R.J.; Burns, A.C.; Lawson, J.D.; Marx, M.A. (2022). CRYSTAL STRUCTURE OF EED WITH MRTX-1919. Protein Data Bank: 7si5. CMCF-ID Health
Kim, H.J.; Edwards, R.A.; Glover, J.N.M. (2022). The crystal structure of RocC, containing FinO domain, 1-126. Protein Data Bank: 7rgt. CMCF-ID Agriculture
Ulaganathan, T.; Cygler, M. (2022). Structure of Bacple_01703. Protein Data Bank: 8ep4. CMCF-ID Agriculture
Ulaganathan, T.; Cygler, M. (2022). Structure of Bacple_01701(H214N), a 6-O-galactose porphyran sulfatase. Protein Data Bank: 7sno. CMCF-ID Agriculture
Ulaganathan, T.; Cygler, M. (2022). Structure of Bacple_01702, a GH29 family glycoside hydrolase. Protein Data Bank: 7snk. CMCF-ID Agriculture
Ulaganathan, T.; Cygler, M. (2022). Structure of Bacple_01701, a 6-O-galactose porphyran sulfatase. Protein Data Bank: 7snj. CMCF-ID Agriculture