Publication Beamlines Strategic Pillar
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] CMCF-ID Health
Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] CMCF-ID Health
Bailey-Elkin, B.A.; Mark, B.L. (2023). PRRSV-1 PLP2 domain. Protein Data Bank: 8ehn. CMCF-ID Health
Frota, N.F.; Pistofidis, A.; Folger, I.B.; Hilvert, D.; Schmeing, T.M. et al. (2023). The condensation domain of surfactin A synthetase C in space group P212121. Protein Data Bank: 8f7g. CMCF-ID Agriculture
Frota, N.; Pistofidis, A.; Folger, I.B.; Hilvert, D.; Schmeing, T.M. et al. (2023). The condensation domain of surfactin A synthetase C in space group P43212. Protein Data Bank: 8f7f. CMCF-ID Agriculture
Kang, R.W.; Thai, E.; Julien, J.P. (2023). Crystal structure of Ky15.11-S100IK Fab in complex with circumsporozoite protein KQPA peptide. Protein Data Bank: 8fb5. CMCF-ID Agriculture
Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAAGA RNA. Protein Data Bank: 8ey8. CMCF-ID Agriculture
Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAGAA RNA. Protein Data Bank: 8ey7. CMCF-ID Agriculture
Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAAAG RNA. Protein Data Bank: 8ey6. CMCF-ID Agriculture
Shahsavan, A.; Gehring, K. (2023). Crystal structure of extracellular domain of CNNM4 from Echinococcus granulosus. Protein Data Bank: 8gk6. CMCF-ID Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Guo, S.; Lin, D. et al. (2023). The Crystal Structure of PPARg from Biortus.. Protein Data Bank: 8wfe. CMCF-ID Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Qi, J.; Li, J. et al. (2023). The Crystal Structure of RSK1 from Biortus.. Protein Data Bank: 8wf4. CMCF-ID Agriculture
Wang, F.; Cheng, W.; Yuan, Z.; Lin, D.; Guo, S. et al. (2023). The Crystal Structure of Mms2 from Biortus. Protein Data Bank: 8wr5. CMCF-ID Agriculture