Publication Beamlines Strategic Pillar
Zhao, Jianhua; Beyrakhova, Ksenia; Liu, Yao; Alvarez, Claudia P.; Bueler, Stephanie A. et al. (2017). Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathogens 13(6) , e1006394. 10.1371/journal.ppat.1006394. CMCF-BM, CMCF-ID Health
Zhang, Wei; Bailey-Elkin, Ben A.; Knaap, Robert C. M.; Khare, Baldeep; Dalebout, Tim J. et al. (2017). Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathogens 13(5) , e1006372. 10.1371/journal.ppat.1006372. CMCF-BM, CMCF-ID Health
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry 222, 113584. 10.1016/j.ejmech.2021.113584. CMCF-BM Health
Ulaganathan, ThirumalaiSelvi; Helbert, William; Kopel, Moran; Banin, Ehud; Cygler, Miroslaw et al. (2018). Structure–function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. Journal of Biological Chemistry 293(11) , 4026-4036. 10.1074/jbc.ra117.001642. CMCF-BM, CMCF-ID Health
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. CMCF-BM Health
Ulaganathan, ThirumalaiSelvi; Banin, Ehud; Helbert, William; Cygler, Miroslaw (2018). Structural and functional characterization of PL28 family ulvan lyase NLR48 from Nonlabens ulvanivorans. Journal of Biological Chemistry 293(29) , 11564-11573. 10.1074/jbc.ra118.003659. CMCF-BM, CMCF-ID Health
Torres, Miguel A.; Hoffarth, Elesha; Eugenio, Luiz; Savtchouk, Julia; Chen, Xue et al. (2016). Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. Journal of Biological Chemistry 291(45) , 23403-23415. 10.1074/jbc.m116.747261. CMCF-BM Health
Stevenson, James; Ngo, Maria; Brandt, Alicia; Weadge, Joel T.; Suits, Michael D. L. et al. (2021). Analysis of Two SusE-Like Enzymes From Bacteroides thetaiotaomicron Reveals a Potential Degradative Capacity for This Protein Family. Frontiers in Microbiology 12. 10.3389/fmicb.2021.645765. CMCF-BM Health
Sokaribo, Akosiererem; Novakovski, Brian A.A.; Cotelesage, Julien; White, Aaron P.; Sanders, David et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517. CMCF-BM, CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. CMCF-BM, CMCF-ID Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. CMCF-BM, CMCF-ID Health
Raczynska, Joanna E.; Shabalin, Ivan G.; Minor, Wladek; Wlodawer, Alexander; Jaskolski, Mariusz et al. (2018). A close look onto structural models and primary ligands of metallo-β-lactamases. Drug Resistance Updates 40, 1-12. 10.1016/j.drup.2018.08.001. CMCF-BM Health
Pluvinage, Benjamin; Grondin, Julie M.; Amundsen, Carolyn; Klassen, Leeann; Moote, Paul E. et al. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications 9(1) . 10.1038/s41467-018-03366-x. CMCF-BM, CMCF-ID Health
Pham, N. T. Hang; Létourneau, Myriam; Fortier, Marlène; Bégin, Gabriel; Al-Abdul-Wahid, M. Sameer et al. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Journal of Biological Chemistry 297(5) , 101308. 10.1016/j.jbc.2021.101308. CMCF-BM Health
Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. CMCF-BM Health