Publication Beamlines Strategic Pillar
Alexander, J. Andrew N.; Chatterjee, Som S.; Hamilton, Stephanie M.; Eltis, Lindsay D.; Chambers, Henry F. et al. (2018). Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. Journal of Biological Chemistry 293(51) , 19854-19865. 10.1074/jbc.ra118.004952. CMCF-BM, CMCF-ID Health
Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. CMCF-BM, CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. CMCF-BM, CMCF-ID Health
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in Mycobacterium tuberculosis , is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. CMCF-BM Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir et al. (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Gebai, Ahmad; Illes, Katalin; Piomelli, Daniele; Nagar, Bhushan et al. (2018). Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America 115(43) , E10032-E10040. 10.1073/pnas.1811759115. CMCF-BM, CMCF-ID Health
Haji-Ghassemi, Omid; Yuchi, Zhiguang; Van Petegem, Filip (2019). The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Molecular Cell 75(1) . 10.1016/j.molcel.2019.04.019. CMCF-BM Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. CMCF-BM, CMCF-ID Health
Hu, Jinhong; Komakula, Aruna; Fraser, Marie E. (2017). Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallographica Section D: Structural Biology 73(8) , 660-671. 10.1107/s2059798317009871. CMCF-BM, CMCF-ID Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. CMCF-BM, CMCF-ID Health
Kgosisejo, Oarabile; Chen, Jian An; Grochulski, Pawel; Tanaka, Takuji (2017). Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships. Biochimica et Biophysica Acta - Proteins and Proteomics 1865(5) , 473-480. 10.1016/j.bbapap.2017.02.004. CMCF-BM, CMCF-ID Health
Labandera, Anne-Marie; Uhrig, R. Glen; Colville, Keaton; Moorhead, Greg B.; Ng, Kenneth K. S. et al. (2018). Structural basis for the preference of the Arabidopsis thaliana phosphatase RLPH2 for tyrosine-phosphorylated substrates. Science Signaling 11(524) , eaan8804. 10.1126/scisignal.aan8804. CMCF-BM Health