| Ferri, Elena; Le Thomas, Adrien; Wallweber, Heidi Ackerly; Day, Eric S.; Walters, Benjamin T. et al. (2020). Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature Communications 11(1) . 10.1038/s41467-020-19974-5. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Stachel, Shawn J.; Ginnetti, Anthony T.; Johnson, Scott A.; Cramer, Paige; Wang, Yi et al. (2020). Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic and Medicinal Chemistry Letters 30(17) , 127403. 10.1016/j.bmcl.2020.127403. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Rescourio, Gwenaella; Gonzalez, Ana Z.; Jabri, Salman; Belmontes, Brian; Moody, Gordon et al. (2019). Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. Journal of Medicinal Chemistry 62(22) , 10258-10271. 10.1021/acs.jmedchem.9b01310. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wrobleski, Stephen T.; Moslin, Ryan; Lin, Shuqun; Zhang, Yanlei; Spergel, Steven et al. (2019). Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. Journal of Medicinal Chemistry 62(20) . 10.1021/acs.jmedchem.9b00444. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Qiu, Luping; Levine, Kymberly; Gajiwala, Ketan S.; Cronin, Ciarán N.; Nagata, Asako et al. (2018). Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers. PLoS ONE 13(6) , e0198374. 10.1371/journal.pone.0198374. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Stöppler, Daniel; Macpherson, Alex; Smith-Penzel, Susanne; Basse, Nicolas; Lecomte, Fabien et al. (2018). Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR. PLoS Biology 16(5) , e2006192. 10.1371/journal.pbio.2006192. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Van Loon, Lisa L.; Nelson, Andrew J.; Banerjee, Neil R. (2018). Will Synchrotron Studies Unlock the Mystery of the Invention of Coinage?. Microscopy and Microanalysis 24(S2) , 560-561. 10.1017/s143192761801499x. |
CLS-APS, IDEAS, SXRMB, VESPERS, VLS-PGM |
Peer-Reviewed Article |
|
| Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Arduini, Connor; Flynn, Trevor; Paetkau, Mark; Brewer, Sharon; Donkor, Kingsley et al. (2018). Synchrotron Characterization of Metal Distributions in Soils Collected in the Greater Kamloops Region, British Columbia, Canada. Microscopy and Microanalysis 24(S2) , 514-515. 10.1017/s1431927618014794. |
CLS-APS, IDEAS |
Conference Proceeding |
Environment |
| Banerjee, Neil R.; Van Loon, Lisa L.; Botor, Ramjay J.; Flynn, Trevor J. (2018). Automated Geochemical and Mineralogical Synchrotron Characterization of Bulk Geological Materials: an Innovation for the Minerals Industry.. Microscopy and Microanalysis 24(S2) , 518-519. 10.1017/s1431927618014812. |
CMCF-BM, IDEAS, VESPERS |
Conference Proceeding |
Environment |
| Banerjee, Neil R.; Van Loon, Lisa L.; Quirt, David (2018). XRF Microscopy and Boron K-edge XANES Analysis of Bulk Rock Samples Associated with Uranium Deposits. Microscopy and Microanalysis 24(S2) , 508-509. 10.1017/s1431927618014769. |
IDEAS, VLS-PGM |
Conference Proceeding |
Environment |