Publication Beamlines Strategic Pillar
De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. CMCF-ID Health
Johal, A. R.; Blackler, R. J.; Alfaro, J. A.; Schuman, B.; Borisova, S. et al. (2013). pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology 24(3) , 237-246. 10.1093/glycob/cwt098. CMCF-ID Health
Parker, Matthew J; Gomery, Kathryn; Richard, Gabrielle; MacKenzie, C Roger; Cox, Andrew D et al. (2014). Structural basis for selective cross-reactivity in a bactericidal antibody against inner core lipooligosaccharide from Neisseria meningitidis†,‡. Glycobiology 24(5) , 442-449. 10.1093/glycob/cwu009. CMCF-ID Health
Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. CMCF-BM, CMCF-ID Health
Singh, Anirudh K.; Pluvinage, Benjamin; Higgins, Melanie A.; Dalia, Ankur B.; Woodiga, Shireen A. et al. (2014). Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus pneumoniae β-galactosidase, BgaA. PLoS Pathogens 10(9) , e1004364. 10.1371/journal.ppat.1004364. CMCF-BM, CMCF-ID Health
Bacik, John-Paul; Tavassoli, Marjan; Patel, Trushar R.; McKenna, Sean A.; Vocadlo, David J. et al. (2014). Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle. Journal of Biological Chemistry 289(7) , 4504-4514. 10.1074/jbc.m113.521633. CMCF-ID Health
Wu, Hong; Zeng, Hong; Lam, Robert; Tempel, Wolfram; Amaya, Maria F. et al. (2011). Structural and Histone Binding Ability Characterizations of Human PWWP Domains. PLoS ONE 6(6) , e18919. 10.1371/journal.pone.0018919. CMCF-ID Health
Kimlicka, Lynn; Lau, Kelvin; Tung, Ching-Chieh; Van Petegem, Filip (2013). Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface. Nature Communications 4(1) , 1506. 10.1038/ncomms2501. CMCF-ID Health
Gould, Alister D.; Shilton, Brian H. (2010). Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate. Journal of Biological Chemistry 285(15) , 11290-11296. 10.1074/jbc.m109.089078. CMCF-ID Health
Wong, Alan H.M.; Zhou, Dongxia; Rini, James M. (2012). The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing. Journal of Biological Chemistry 287(44) , 36804-36813. 10.1074/jbc.m112.398842. CMCF-ID Health
Loewen, Peter C.; Didychuk, Allison L.; Switala, Jacek; Perez-Luque, Rosa; Fita, Ignacio et al. (2012). Structure ofPisum sativumRubisco with bound ribulose 1,5-bisphosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(1) , 10-14. 10.1107/s1744309112047549. CMCF-ID Health
Cherney, Maia M.; Zhang, Yanfei; James, Michael N.G.; Weiner, Joel H. (2012). Structure–activity characterization of sulfide:quinone oxidoreductase variants. Journal of Structural Biology 178(3) , 319-328. 10.1016/j.jsb.2012.04.007. CMCF-ID Health
Cherney, Maia M.; Cherney, Leonid T.; Garen, Craig R.; James, Michael N.G. (2011). The Structures of Thermoplasma volcanium Phosphoribosyl Pyrophosphate Synthetase Bound to Ribose-5-Phosphate and ATP Analogs. Journal of Molecular Biology 413(4) , 844-856. 10.1016/j.jmb.2011.09.007. CMCF-ID Health
Tonkin, Michelle L.; Roques, Magali; Lamarque, Mauld H.; Pugnière, Martine; Douguet, Dominique et al. (2011). Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide. Science 333(6041) , 463-467. 10.1126/science.1204988. CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Tao, Limei; Zhang, Linhua; Menard, Robert et al. (2011). Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex. Journal of Biological Chemistry 286(12) , 10735-10743. 10.1074/jbc.m110.194423. CMCF-ID Health