Publication Beamlines Strategic Pillar
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. CMCF-BM, CMCF-ID Health
Mabanglo, Mark F.; Leung, Elisa; Vahidi, Siavash; Seraphim, Thiago V.; Eger, Bryan T. et al. (2019). ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Communications Biology 2(1) . 10.1038/s42003-019-0656-3. CMCF-BM Health
Rescourio, Gwenaella; Gonzalez, Ana Z.; Jabri, Salman; Belmontes, Brian; Moody, Gordon et al. (2019). Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. Journal of Medicinal Chemistry 62(22) , 10258-10271. 10.1021/acs.jmedchem.9b01310. CMCF-ID Health
McCallum, Matthew; Benlekbir, Samir; Nguyen, Sheryl; Tammam, Stephanie; Rubinstein, John L. et al. (2019). Multiple conformations facilitate PilT function in the type IV pilus. Nature Communications 10(1) . 10.1038/s41467-019-13070-z. CMCF-ID Health
Tarry, Michael J.; Harmel, Christoph; Taylor, James A.; Marczynski, Gregory T.; Schmeing, T. Martin et al. (2019). Structures of GapR reveal a central channel which could accommodate B-DNA. Scientific Reports 9(1) . 10.1038/s41598-019-52964-2. CMCF-ID Health
Reimer, Janice M.; Eivaskhani, Maximilian; Harb, Ingrid; Guarné, Alba; Weigt, Martin et al. (2019). Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science 366(6466) , eaaw4388. 10.1126/science.aaw4388. CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. CMCF-BM, CMCF-ID Health
Li, Zhijie; Tomlinson, Aidan CA; Wong, Alan HM; Zhou, Dongxia; Desforges, Marc et al. (2019). The human coronavirus HCoV-229E S-protein structure and receptor binding. eLife 8. 10.7554/elife.51230. CMCF-ID Health
Hettle, Andrew G.; Hobbs, Joanne K.; Pluvinage, Benjamin; Vickers, Chelsea; Abe, Kento T. et al. (2019). Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species. Communications Biology 2(1) . 10.1038/s42003-019-0721-y. CMCF-ID Environment