Pushie, M. J.; Kelly, M. E.; Hackett, M. J. (2018). Direct label-free imaging of brain tissue using synchrotron light: a review of new spectroscopic tools for the modern neuroscientist. Analyst. The 143(16) , 3761-3774. 10.1039/c7an01904a. |
MID-IR, SXRMB |
Peer-Reviewed Article |
Health |
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in
Mycobacterium tuberculosis
, is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Pluvinage, Benjamin; Grondin, Julie M.; Amundsen, Carolyn; Klassen, Leeann; Moote, Paul E. et al. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications 9(1) . 10.1038/s41467-018-03366-x. [PDB: 5t9a, 5t9x, 5ta0, 5ta1, 5ta5, 5ta7, 5ta9] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Workman, Sean D.; Worrall, Liam J.; Strynadka, Natalie C. J. (2018). Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling. Nature Communications 9(1) . 10.1038/s41467-018-03547-8. [PDB: 6cb2] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Zhang, Heng; Zhou, Bo; Qin, Su; Xu, Jing; Harding, Rachel et al. (2018). Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. Genes & Development 32(5-6) , 341-346. 10.1101/gad.311639.118. [PDB: 6cko] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dementiev, Alexey; Silva, Abel; Yee, Calvin; Li, Zhe; Flavin, Michael T. et al. (2018). Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors. Blood advances 2(5) , 549-558. 10.1182/bloodadvances.2018016337. [PDB: 6b74] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Reid, Joel W.; Kaduk, James A.; Matei, Lidia (2018). The crystal structure of MoO2(O2)H2O. Powder Diffraction 33(1) , 49-54. 10.1017/s0885715618000118. |
CMCF-BM |
Peer-Reviewed Article |
Health |
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] |
CMCF-ID |
Peer-Reviewed Article |
Health |
McAllister, Laura A.; Butler, Christopher R.; Mente, Scot; O’Neil, Steven V.; Fonseca, Kari R. et al. (2018). Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. Journal of Medicinal Chemistry 61(7) , 3008-3026. 10.1021/acs.jmedchem.8b00070. [PDB: 6bq0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Xu, Chao; Liu, Ke; Lei, Ming; Yang, Ally; Li, Yanjun et al. (2018). DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure 26(1) , 85-95.e3. 10.1016/j.str.2017.11.022. [PDB: 5w9q] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Vance, Tyler D.R.; Graham, Laurie A.; Davies, Peter L. (2018). An ice‐binding and tandem beta‐sandwich domain‐containing protein in
Shewanella frigidimarina
is a potential new type of ice adhesin. FEBS Journal 285(8) , 1511-1527. 10.1111/febs.14424. [PDB: 6bg8] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Agrawal, Sumit; Schart-Morén, Nadine; Liu, Wei; Ladak, Hanif M.; Rask-Andersen, Helge et al. (2018). The secondary spiral lamina and its relevance in cochlear implant surgery. Upsala Journal of Medical Sciences 123(1) , 9-18. 10.1080/03009734.2018.1443983. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mahoney, Sarah J.; Narayan, Sridhar; Molz, Lisa; Berstler, Lauren A.; Kang, Seong A. et al. (2018). A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nature Communications 9(1) . 10.1038/s41467-018-03035-z. [PDB: 6bt0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Leighton, T. L.; Mok, M. C.; Junop, M. S.; Howell, P. L.; Burrows, L. L. et al. (2018). Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function. Scientific Reports 8(1) . 10.1038/s41598-018-20925-w. [PDB: 5uvr] |
CMCF-ID |
Peer-Reviewed Article |
Health |