Sima Zeinali Danalou (2022). In-situ Internal Study of Liquid Binder Penetration and Nucleation Dynamics in Wet Granulation of Pharmaceutical Powders using Synchrotron X-ray Imaging. Supervisor: Zhang, Lifeng. Saskatchewan, Canada: University of Saskatchewan. https://harvest.usask.ca/handle/10388/14247. |
BMIT-BM |
Masters Thesis |
Health |
Danalou, Sima Zeinali; Ding, Xiao Fan; Zhu, Ning; Emady, Heather N.; Zhang, Lifeng et al. (2022). 4D study of liquid binder penetration dynamics in pharmaceutical powders using synchrotron X-ray micro computed tomography. International Journal of Pharmaceutics 627, 122192. 10.1016/j.ijpharm.2022.122192. |
BMIT-BM |
Peer-Reviewed Article |
Health |
Li, Hao; Agrawal, Sumit; Rohani, Seyed Alireza; Zhu, Ning; Cacciabue, Daniela I. et al. (2022). Unlocking the human inner ear for therapeutic intervention. Scientific Reports 12, 18508. 10.1038/s41598-022-22203-2. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Harrison, Kim D; Sales, Erika; Hiebert, Beverly D; Panahifar, Arash; Zhu, Ning et al. (2022). Direct Assessment of Rabbit Cortical Bone Basic Multicellular Unit Longitudinal Erosion Rate: A
4D
Synchrotron‐Based Approach. Journal of Bone and Mineral Research 37(11) , 2244-2258. 10.1002/jbmr.4700. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Scheu, Karlton Irie (2022). Dissecting the biophysical properties and DNA-binding specificity of the ETV6 transcription factor. Supervisor: McIntosh, Lawrence. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/82634. |
CMCF |
Doctoral Thesis |
Health |
van Vliet, Vera J. E.; Huynh, Nhan; Palà, Judith; Patel, Ankoor; Singer, Alex et al. (2022). Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathogens 18(12) , e1011065. 10.1371/journal.ppat.1011065. |
CMCF |
Peer-Reviewed Article |
Health |
Mabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Leung, Elisa; Chuang, Stephanie H.W. et al. (2022). Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure . 10.1016/j.str.2022.12.002. [PDB: 7uvm, 7uvn, 7uvr, 7uvu, 7uw0] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Gheorghita, Andreea A.; Li, Yancheng E.; Kitova, Elena N.; Bui, Duong T.; Pfoh, Roland et al. (2022). Structure of the AlgKX modification and secretion complex required for alginate production and biofilm attachment in Pseudomonas aeruginosa. Nature Communications 13(1) . 10.1038/s41467-022-35131-6. [PDB: 7ula] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. [PDB: 8csb, 8csc, 8csd, 8cse, 8csf] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochimica et Biophysica Acta - General Subjects 1866(11) , 130217. 10.1016/j.bbagen.2022.130217. [PDB: 7uqv] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Lorente Cobo, Neil; Sibinelli-Sousa, Stephanie; Biboy, Jacob; Vollmer, Waldemar; Bayer-Santos, Ethel et al. (2022). Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold. Journal of Biological Chemistry 298(11) , 102556. 10.1016/j.jbc.2022.102556. [PDB: 7uo3, 7uo8] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Kuttiyatveetil, Jijin R.A.; Soufari, Heddy; Dasovich, Morgan; Uribe, Isabel R.; Mirhasan, Manija et al. (2022). Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Reports 41(4) , 111529. 10.1016/j.celrep.2022.111529. [PDB: 7sz2, 7sz3] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Hallett, Robin M.; Bonfill-Teixidor, Ester; Iurlaro, Raffaella; Arias, Alexandra; Raman, Swetha et al. (2022). Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment. Clinical Cancer Research 29(4) , 791-804. 10.1158/1078-0432.ccr-21-1888. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Candito, David A.; Simov, Vladimir; Gulati, Anmol; Kattar, Solomon; Chau, Ryan W. et al. (2022). Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry 65(24) , 16801-16817. 10.1021/acs.jmedchem.2c01605. [PDB: 8e80] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Luan, Xiaodong; Li, Xinming; Li, Yufan; Su, Gengchen; Yin, Wanchao et al. (2022). Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Science Bulletin 67(22) , 2327-2335. 10.1016/j.scib.2022.10.021. [PDB: 7xwz] |
CMCF-ID |
Peer-Reviewed Article |
Health |