Publication Beamlines Strategic Pillar
Zhang, Qi; Fan, Lixin; Hou, Feng; Dong, Aiping; Wang, Yun-Xing et al. (2015). New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins. Scientific Reports 5(1) . 10.1038/srep15660. [PDB: 4z30] CMCF-ID Health
Yuchi, Zhiguang; Yuen, Siobhan M. Wong King; Lau, Kelvin; Underhill, Ainsley Q.; Cornea, Razvan L. et al. (2015). Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant. Nature Communications 6(1) . 10.1038/ncomms8947. CMCF-ID Health
Xu, Chao; Li, Zhihong; He, Hao; Wernimont, Amy; Li, Yanjun et al. (2015). Crystal structure of human nuclear pore complex component NUP43. FEBS Letters 589(21) , 3247-3253. 10.1016/j.febslet.2015.09.008. [PDB: 4i79] CMCF-BM Health
Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka et al. (2015). Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3. Nuclear Instruments and Methods in Physics Research. Section A: Accelerators. Spectrometers. Detectors and Associated Equipment 775, 1-4. 10.1016/j.nima.2014.11.088. BMIT-BM, BMIT-ID Health
White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A. et al. (2015). Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. ACS Chemical Biology 10(5) , 1198-1208. 10.1021/cb500757u. [PDB: 4ofb] CMCF-BM, CMCF-ID Health
Wan, Honghe; Schroeder, Gretchen M.; Hart, Amy C.; Inghrim, Jennifer; Grebinski, James et al. (2015). Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms. ACS Medicinal Chemistry Letters 6(8) , 850-855. 10.1021/acsmedchemlett.5b00226. [PDB: 5cf8] CMCF-ID Health
Volkers, Gesa; Worrall, Liam J; Kwan, David H; Yu, Ching-Ching; Baumann, Lars et al. (2015). Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nature Structural and Molecular Biology 22(8) , 627-635. 10.1038/nsmb.3060. [PDB: 5bo6, 5bo7, 5bo8] CMCF-BM, CMCF-ID Health
van Straaten, Karin E.; Kuttiyatveetil, Jijin R. A.; Sevrain, Charlotte M.; Villaume, Sydney A.; Jiménez-Barbero, Jesús et al. (2015). Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues. Journal of the American Chemical Society 137(3) , 1230-1244. 10.1021/ja511204p. [PDB: 4rpg, 4rph, 4rpj, 4rpk, 4rpl] CMCF-ID Health
Vadlamani, Grishma; Thomas, Misty D.; Patel, Trushar R.; Donald, Lynda J.; Reeve, Thomas M. et al. (2015). The β-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide. Journal of Biological Chemistry 290(5) , 2630-2643. 10.1074/jbc.m114.618199. [PDB: 4wkm] CMCF-ID Health
Ukkonen, H.; Kumar, S.; Mikkonen, J.; Salo, T.; Singh, S.P. et al. (2015). Changes in the microenvironment of invading melanoma and carcinoma cells identified by FTIR imaging. Vibrational Spectroscopy 79, 24-30. 10.1016/j.vibspec.2015.04.005. MID-IR Health
Tokarski, John S.; Zupa-Fernandez, Adriana; Tredup, Jeffrey A.; Pike, Kristen; Chang, ChiehYing et al. (2015). Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. Journal of Biological Chemistry 290(17) , 11061-11074. 10.1074/jbc.m114.619502. [PDB: 4wov] CMCF-ID Health
Taylor, Alexander M.; Vaswani, Rishi G.; Gehling, Victor S.; Hewitt, Michael C.; Leblanc, Yves et al. (2015). Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. ACS Medicinal Chemistry Letters 7(2) , 145-150. 10.1021/ml500411h. [PDB: 4z1s] CMCF-ID Health
Szewczyk, Paul; Tao, Houchao; McGrath, Aaron P.; Villaluz, Mark; Rees, Steven D. et al. (2015). Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallographica Section D Biological Crystallography 71(3) , 732-741. 10.1107/s1399004715000978. [PDB: 4q9i, 4q9j, 4q9l] CMCF-ID Health
Solomonson, Matthew; Setiaputra, Dheva; Makepeace, Karl A.T.; Lameignere, Emilie; Petrotchenko, Evgeniy V. et al. (2015). Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism. Structure 23(3) , 571-583. 10.1016/j.str.2015.01.002. [PDB: 4wj1, 4wj2] CMCF-BM Health
Sobhanifar, Solmaz; Worrall, Liam James; Gruninger, Robert J.; Wasney, Gregory A.; Blaukopf, Markus et al. (2015). Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid α-glycosyltransferase. Proceedings of the National Academy of Sciences of the United States of America 112(6) , E576-E585. 10.1073/pnas.1418084112. [PDB: 4x6l, 4x7m, 4x7p, 4x7r] CMCF-BM Health