Williamson, Michael R.; Dietrich, Kristen; Hackett, Mark J.; Caine, Sally; Nadeau, Colby A. et al. (2017). Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage. Stroke 48(1) , 195-203. 10.1161/strokeaha.116.015404. |
MID-IR |
Peer-Reviewed Article |
Health |
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. [PDB: 5uam, 5uas] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Pratt, Isaac Vorster; Cooper, David Michael Lane (2017). A method for measuring the three-dimensional orientation of cortical canals with implications for comparative analysis of bone microstructure in vertebrates. Micron 92, 32-38. 10.1016/j.micron.2016.10.006. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Olubamiji, Adeola D.; Zhu, Ning; Chang, Tuanjie; Nwankwo, Chijioke K.; Izadifar, Zohreh et al. (2017). Traditional Invasive and Synchrotron-Based Noninvasive Assessments of Three-Dimensional-Printed Hybrid Cartilage Constructs In Situ. Tissue Engineering - Part C: Methods 23(3) , 156-168. 10.1089/ten.tec.2016.0368. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Moen, Spencer O.; Edwards, Thomas E.; Dranow, David M.; Clifton, Matthew C.; Sankaran, Banumathi et al. (2017). Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Scientific Reports 7(1) . 10.1038/s41598-017-00367-6. [PDB: 3tze] |
CMCF-ID |
Peer-Reviewed Article |
Health |
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mallette, Evan; Kimber, Matthew S. (2017). A Complete Structural Inventory of the Mycobacterial Microcompartment Shell Proteins Constrains Models of Global Architecture and Transport. Journal of Biological Chemistry 292(4) , 1197-1210. 10.1074/jbc.m116.754093. [PDB: 5l37, 5l38, 5l39, 5suh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Kumar, Saroj; Liu, Xia; Borondics, Ferenc; Xiao, Qunfeng; Feng, Renfei et al. (2017). Insights into Biochemical Alteration in Cancer-Associated Fibroblasts by using Novel Correlative Spectroscopy. ChemistryOpen 6(1) , 149-157. 10.1002/open.201600102. |
MID-IR, SXRMB, VESPERS |
Peer-Reviewed Article |
Health |
King, Dustin T.; Wasney, Gregory A.; Nosella, Michael; Fong, Anita; Strynadka, Natalie C.J. et al. (2017). Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B. Journal of Biological Chemistry 292(3) , 979-993. 10.1074/jbc.m116.718403. [PDB: 5hl9, 5hla, 5hlb, 5hld] |
CMCF-ID |
Peer-Reviewed Article |
Health |