Publication Beamlines Strategic Pillar
Fodje, Michel; Mundboth, Kiran; Labiuk, Shaunivan; Janzen, Kathryn; Gorin, James et al. (2020). Macromolecular crystallography beamlines at the Canadian Light Source: building on success. Acta Crystallographica Section D: Structural Biology 76(7) . 10.1107/s2059798320007603. CMCF-BM, CMCF-ID Health
Gagarina, Varvara; Bojagora, Anna; Lacdao, Ira Kay; Luthra, Niharika; Pfoh, Roland et al. (2020). Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2. Journal of Molecular Biology 432(4) . 10.1016/j.jmb.2019.12.026. [PDB: 6p5l] CMCF-ID Health
Geiger, Michael; Brown, Chris; Wichers, Jan Stephan; Strauss, Jan; Lill, Andrés et al. (2020). Structural Insights Into PfARO and Characterization of its Interaction With PfAIP. Journal of Molecular Biology 432(4) . 10.1016/j.jmb.2019.12.024. CMCF-ID Health
Gorelik, Alexei; Labriola, Jonathan M.; Illes, Katalin; Nagar, Bhushan (2020). Crystal structure of the nucleotide‐metabolizing enzyme NTPDase4. Protein Science 29(10) . 10.1002/pro.3926. [PDB: 6wg5] CMCF-ID Health
Grant, Benjamin M. M.; Enomoto, Masahiro; Back, Sung-In; Lee, Ki-Young; Gebregiworgis, Teklab et al. (2020). Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety. Science Signaling 13(625) , eaaz0344. 10.1126/scisignal.aaz0344. [PDB: 6os4] CMCF-ID Health
Harikrishnan, Lalgudi S.; Gill, Patrice; Kamau, Muthoni G.; Qin, Lan-Ying; Ruan, Zheming et al. (2020). Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists. Bioorganic and Medicinal Chemistry Letters 30(12) , 127204. 10.1016/j.bmcl.2020.127204. [PDB: 6xae] CMCF-ID Health
Helpard, Luke; Li, Hao; Rask-Andersen, Helge; Ladak, Hanif M.; Agrawal, Sumit K. et al. (2020). Characterization of the human helicotrema: implications for cochlear duct length and frequency mapping. Journal of Otolaryngology - Head and Neck Surgery 49(1) , 2. 10.1186/s40463-019-0398-8. BMIT-ID Health
Hersch, Steven J.; Watanabe, Nobuhiko; Stietz, Maria Silvina; Manera, Kevin; Kamal, Fatima et al. (2020). Envelope stress responses defend against type six secretion system attacks independently of immunity proteins. Nature Microbiology 5(5) . 10.1038/s41564-020-0672-6. [PDB: 6v98] CMCF-BM Health
Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] CMCF-BM Health
Huhn, Annissa J.; Gardberg, Anna S.; Poy, Florence; Brucelle, Francois; Vivat, Valerie et al. (2020). Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. ChemMedChem 15(11) . 10.1002/cmdc.202000007. [PDB: 6v8n] CMCF-ID Health
Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L. et al. (2020). Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Bioorganic and Medicinal Chemistry Letters 30(21) , 127495. 10.1016/j.bmcl.2020.127495. [PDB: 7jou] CMCF-ID Health
Jiang, Ying-Ying; Wang, Zhi-Qiang; Chen, Jia-Tang; Li, Jun; Zhu, Ying-Jie et al. (2020). Tracking the interaction of drug molecules with individual mesoporous amorphous calcium phosphate/ATP nanocomposites – an X-ray spectromicroscopy study. Physical Chemistry Chemical Physics 22(23) . 10.1039/d0cp00797h. SGM, SM, SXRMB, VLS-PGM Health
Jones, Carys S.; Sychantha, David; Howell, P. Lynne; Clarke, Anthony J. (2020). Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. Journal of Biological Chemistry 295(24) , jbc.RA120.013108. 10.1074/jbc.ra120.013108. [PDB: 6wn9] CMCF-BM Health
Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. CMCF Health
Li, Franco K.K.; Rosell, Federico I.; Gale, Robert T.; Simorre, Jean-Pierre; Brown, Eric D. et al. (2020). Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. Journal of Biological Chemistry 295(9) , 2629-2639. 10.1074/jbc.ra119.011469. [PDB: 6uex, 6uf3, 6uf5, 6uf6] CMCF-ID Health