Publication Beamlines Strategic Pillar
Afroz, Sharmin; Brownlie, Robert; Fodje, Michel; van Drunen Littel-van den Hurk, Sylvia (2019). The bovine herpesvirus-1 major tegument protein, VP8, interacts with host HSP60 concomitant with deregulation of mitochondrial function. Virus Research 261, 37-49. 10.1016/j.virusres.2018.12.006. Health
Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] CMCF-BM, CMCF-ID Health
Atake, Oghenevwogaga J.; Cooper, David M.L.; Eames, B. Frank (2019). Bone-like features in skate suggest a novel elasmobranch synapomorphy and deep homology of trabecular mineralization patterns. Acta Biomaterialia 84, 424-436. 10.1016/j.actbio.2018.11.047. BMIT-ID Health
Chong, Pek Y.; Shotwell, J. Brad; Miller, John; Price, Daniel J.; Maynard, Andy et al. (2019). Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. Journal of Medicinal Chemistry 62(7) , 3254-3267. 10.1021/acs.jmedchem.8b01719. [PDB: 6mvo] CMCF-ID Health
Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Stachura, Sylwia; Weigelt, Carolyn A. et al. (2019). Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists. ACS Medicinal Chemistry Letters 10(3) , 367-373. 10.1021/acsmedchemlett.9b00010. [PDB: 6nx1] CMCF-ID Health
Gytz, Heidi; Liang, Jason; Liang, Yingke; Gorelik, Alexei; Illes, Katalin et al. (2019). The structure of mammalian β‐mannosidase provides insight into β‐mannosidosis and nystagmus. FEBS Journal 286(7) . 10.1111/febs.14731. [PDB: 6ddt, 6ddu] CMCF-ID Health
Hitchcock, Adam P.; Wang, Xiaoyue; Grandfield, Kathryn; Everett, James; Collingwood, Joanna F. et al. (2019). Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies. Microscopy Today 27(2) , 12-19. 10.1017/s1551929518001256. SM Health
Liu, Yanli; Qin, Su; Chen, Tsai-Yu; Lei, Ming; Dhar, Shilpa S. et al. (2019). Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nature Communications 10(1) . 10.1038/s41467-018-07906-3. [PDB: 6mlc] CMCF-ID Health
Luan, Xiaojie; Tam, Julian S.; Belev, George; Jagadeeshan, Santosh; Murray, Brendan et al. (2019). Nebulized hypertonic saline triggers nervous system-mediated active liquid secretion in cystic fibrosis swine trachea. Scientific Reports 9(1) , 540. 10.1038/s41598-018-36695-4. BMIT-BM Health
McDougall, Matthew; Francisco, Olga; Harder-Viddal, Candice; Roshko, Roy; Heide, Fabian et al. (2019). Proteinaceous Nano container Encapsulate Polycyclic Aromatic Hydrocarbons. Scientific Reports 9(1) . 10.1038/s41598-018-37323-x. CMCF-ID Health
Perez-Borrajero, Cecilia; Lin, Chang Sheng-Huei; Okon, Mark; Scheu, Karlton; Graves, Barbara J. et al. (2019). The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. Journal of Molecular Biology 431(3) . 10.1016/j.jmb.2018.12.011. [PDB: 6da1] CMCF-BM Health
Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] CMCF-ID Health
Ryan, Patrick; Forrester, Taylor J.B.; Wroblewski, Charles; Kenney, Tristan M.G.; Kitova, Elena N. et al. (2019). The small RbcS-like domains of the β-carboxysome structural protein CcmM bind RubisCO at a site distinct from that binding the RbcS subunit. Journal of Biological Chemistry 294(8) , 2593-2603. 10.1074/jbc.ra118.006330. [PDB: 6mr1] CMCF-ID Health
Schart-Morén, Nadine; Agrawal, Sumit K.; Ladak, Hanif M.; Li, Hao; Rask-Andersen, Helge et al. (2019). Effects of Various Trajectories on Tissue Preservation in Cochlear Implant Surgery: A Micro-Computed Tomography and Synchrotron Radiation Phase-Contrast Imaging Study. Ear and Hearing 40(2) , 393–400. 10.1097/aud.0000000000000624. BMIT-ID Health
Sengupta, Shomit; Giaime, Emilie; Narayan, Sridhar; Hahm, Seung; Howell, Jessica et al. (2019). Discovery of NV-5138, the first selective Brain mTORC1 activator. Scientific Reports 9(1) , 4107. 10.1038/s41598-019-40693-5. [PDB: 6n0m] CMCF-ID Health