| Wrobleski, Stephen T.; Moslin, Ryan; Lin, Shuqun; Zhang, Yanlei; Spergel, Steven et al. (2019). Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. Journal of Medicinal Chemistry 62(20) . 10.1021/acs.jmedchem.9b00444. [PDB: 6nzq, 6nzr] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Shi, R. (2019). Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M,LC-S30bR]. Protein Data Bank: 6my5. |
CMCF-ID |
PDB Deposition |
Health |
| Shi, R.; Picard, M.-E.; Manenda, M. (2019). Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR]. Protein Data Bank: 6my4. |
CMCF-ID |
PDB Deposition |
Health |
| Shi, R.; Picard, M.-E.; Manenda, M.S. (2019). Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M]. Protein Data Bank: 6mxs. |
CMCF-ID |
PDB Deposition |
Health |
| Shi, R. (2019). Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M]. Protein Data Bank: 6mxr. |
CMCF-ID |
PDB Deposition |
Health |
| Schrag, Joseph D.; Picard, Marie-Ève; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason et al. (2019). Binding symmetry and surface flexibility mediate antibody self-association. mAbs 11(7) , 1-19. 10.1080/19420862.2019.1632114. [PDB: 6mxr, 6mxs, 6my4, 6my5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Edwards, T.E.; Abendroth, J.; Safford, K.; Chun, L. (2019). Crystal structure of KIT1 in complex with DP2976 via co-crystallization. Protein Data Bank: 6mob. |
CMCF-ID |
PDB Deposition |
Health |
| Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sack, J. (2019). Crystal structure of RAR-related orphan receptor C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor. Protein Data Bank: 6p9f. |
CMCF-ID |
PDB Deposition |
Health |
| Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng et al. (2019). Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Bioorganic and Medicinal Chemistry Letters 29(16) . 10.1016/j.bmcl.2019.06.036. [PDB: 6p9f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Huang, J.; Fraser, M.E. (2019). ADP bound to L227bF mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase. Protein Data Bank: 6no4. |
CMCF-ID |
PDB Deposition |
Health |
| Huang, J.; Fraser, M.E. (2019). ADP bound to V113bL mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase. Protein Data Bank: 6no3. |
CMCF-ID |
PDB Deposition |
Health |
| Huang, J.; Fraser, M.E. (2019). ADP bound to K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase. Protein Data Bank: 6no2. |
CMCF-ID |
PDB Deposition |
Health |